Natural History.
      (Found in many plants, Chen. v., Crateg. ox., Phal. imp., Pyr. com., Arn., Cotyl. u., Fag. syl., &c., and in herring-brine.) Solution.

      Ankles, pains in.
      Rheumatic fever.
      Wrists, pains in.

      Trimethyl., which is prepared from herring-brine among other sources, has a very unpleasant and penetrating fish-like odor.
      At one time it was regarded as a panacea in cases of acute rheumatism.
      Experiments on patients and others show that it diminishes the amount of urea excreted.
      Hansen gives these as characteristics: great pains in wrist-joints, also great restlessness, pains in ankle-joints from standing worse slight movement.
      C. Carleton Smith (H. P., vi. 432) gives these: "Rheumatism, when the needle held in the fingers gets so heavy she cannot sew." "Copious diarrhoea with pains in ankle-joints but not in wrists, thirst for large quantities of cold water (like Bry.)."